Abstract
This study documents the success rate and risks of laparoscopic local injection of methotrexate in the unruptured tubal pregnancy. This was a prospective study conducted in two centres, King Abdulaziz University Hospital and Dr Erfan & Bagedo Hospital, Jeddah, Saudi Arabia. Twenty-one patients with an intact tubal pregnancy were selected for laparoscopic local treatment with the use of a single injection of 12·5 mg of methotrexate into the ectopic site at the time of diagnostic laparoscopy. In 80·9% (17 patients), serum g -hCG level decreased to the nonpregnant level with no further intervention and the patients recovered without any serious side effect. In 19·9% (four patients) mini-laparotomy was indicated because of a rising g -hCG. Local methotrexate therapy in an early intact tubal ectopic at the time of laparoscopy is a possible alternative to surgery in selected cases. It also has some advantage over systemic (intramuscular) methotrexate as it avoids potentially serious side effects.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
