Laparoscopic management of an invasive mole combined with iatrogenic uterine perforation

Abstract

ObjectiveHydatidiform mole is a common placental proliferative disease which is harmful to women's reproductive health. It is characterized by abnormal fertilization and subsequent trophoblastic proliferation. Invasive mole originates from hydatidiform mole, but its pathogenesis is still unclear. It has been reported that hydatidiform mole mainly develop with the uterine cavity. Invasive mole caused by iatrogenic uterine perforation is rarely reported. Here, we reported a rare case of invasive mole initially presented with uterine iatrogenic perforation after suction curettage. Case reportA 25-year-old nulliparous woman (gravida 1 para 0) who presented with acute hemoperitoneum was admitted to our hospital. Her clinical manifestation was mimicked by uterine iatrogenic perforation, and mole tissues were found on the left posterior wall of uterus. Laparoscopic management was performed to clear the lesions away thoroughly and repair the uterus. The operation was successful, and the reproductive function was preserved. The patient gave a birth to a healthy baby four years after the operation. ConclusionLaparoscopic minimally technique plays a very good therapeutic effect on invasive mole initially presented with iatrogenic uterine perforation.