Abstract

Introduction.Living donor liver transplantation has proved to be an effective, safe and radical treatment modality for patients with end-stage liver diseases. Left lateral section (LLS) of donor’s liver is used in pediatric recipients. Laparoscopic LLS procurement was fi rst described by D. Cherqui in 2002. At present, this technique is routinely used only by 5 hospitals in the world. However, up to date, some authors consider it to be a new standard to perform such a surgery in living donors.Aim.To analyze the fi rst Russian experience in laparoscopic left lateral sectionectomy (LapLLS) in living related donor.Materials and methods.From May to September 2016 fi ve LapLLS were performed in living donors. In all cases donors were women (mothers in 4 cases and aunt in 1 case). Recipients were children aged from 6 months through 3 years with body mass from 5.6 to 12.5 kg. Liver transection was carried out under conditions of maintained blood supply. Parenchymal transection was performed using a harmonic scalpel, bipolar coagulation and ultrasound dissection.Results. Average donor age was 32 ± 5 years. Average operation time was 287 ± 16 min. Average LLS graft weight was 220 ± 16 g. Intraoperative blood loss did not exceed 100 ml (95 ± 5 ml). Donors were discharged on the 3rd–4th post-op day. There were no postoperative complications in donors. Recipients were also characterized by a standard course of the postoperative period.Conclusion.LapLLS is an effective and safe method with several advantages. Primarily, these are early rehabilitation of the donors and shortening of the hospital stay, which are important for the quick return to normal way of live. Excellent visualization of anatomical structures, including vascular and biliary ones, allows performing precise selection. In addition, good cosmetic effect is also an important aspect.

Highlights

  • Living donor liver transplantation has proved to be an effective, safe and radical treatment modality for patients with end-stage liver diseases

  • Laparoscopic Left Lateral Sectionectomy (LapLLS) for focal diseases is gradually becoming a routine practice of the major surgical centers specializing in hepatobiliary surgery

  • Left lateral sectionectomy in living donor seems to be an optimal way for the introduction of laparoscopic techniques into practice of living related donation

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Summary

Introduction

Living donor liver transplantation has proved to be an effective, safe and radical treatment modality for patients with end-stage liver diseases. LapLLS is an effective and safe method with several advantages These are early rehabilitation of the donors and shortening of the hospital stay, which are important for the quick return to normal way of live. Partial liver transplantation from a living donor as an alternative to the whole organ transplantation from a deceased donor enters into practice widely in the European and Russian transplant centers. It remains to be the main method in the Asian region. The advantages of partial liver transplantation in children and adults are the possibility of careful planning of the operation and preoperative recipient preparation [3, 4]

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