Laparoscopic breast-conserving surgery combined with radiofrequency ablation to treat the early-stage breast cancer

Abstract

Objective To analyze the clinical efficacy of the laparoscopic breast-conserving surgery combined with radiofrequency ablation to treat the early-stage breast cancer. Methods We collected 55 patients diagnosed early-stage breast cancer in retrospect, which started from January 2014 to December 2016. Twenty-seven of them were performed the laparoscopic breast-conserving surgery combined with radiofrequency ablation while others went through laparoscopic breast-conserving surgery without radiofrequency ablation. Meanwhile, we adopted the student t-test and the chi-square test to compare results of two groups. More specific, the main indexes of this study are including the post-operative local recurrence, the incidence of fat liquefaction or the incision-infection, operation time, post-operative hospital stay and the hospitalization expense. Results The laparoscopic breast-conserving surgery combined with radiofrequency ablation group had low local-recurrence than the laparoscopic breast-conserving surgery group (0 and 7.69%). Additionally, there were no statistical differences between two groups in the incidence of fat liquefaction. However, The laparoscopic breast-conserving surgery combined with radiofrequency ablation group had more hospitalization expense than the laparoscopic breast-conserving surgery group [(4.1±0.7) ten thousand yuan and (2.3±0.6) ten thousand yuan, P<0.05]. Conclusions Although the laparoscopic breast-conserving surgery combined with radiofrequency ablation group remarkably increased the hospitalization expense because of the utility of the radiofrequency ablation related apparatus, it may provide the probability of shaving more residual tumor cell and may low down the recurrence, especially not rising up the incidence of the post-operative fat liquefaction. Therefore, this surgery method might be one of the potential developments in the minimal-invasive of early stage breast cancer. Key words: Breast neoplasms; Laparoscope; Therapies, investigational; Radiofrequency ablation; Fat liquefaction; Breast-conserving surgery