Abstract

A 71-year-old Japanese man on hemodialysis for chronic renal failure underwent EGD screening. He had been taking lanthanum carbonate for 6 years to treat hyperphosphatemia. EGD showed diffuse deposition of white microgranules in the gastric body (A). In addition, white villi were observed in the duodenal second portion (B). Histologic examination of the duodenal biopsy specimen from the duodenal mucosa showed a fine, amorphous, eosinophilic material (C) that was also seen in the gastric mucosa. A diagnosis of lanthanum phosphate deposition in the duodenal and gastric mucosa was made after analysis by scanning electron microscopy and elemental mapping showing the colocation of lanthanum and phosphate (D).

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