Abstract
The human red cell contains four major glycoproteins : sialoglycoprotein or PAS 1; Band III; PAS 2 and PAS 3. With the exception of Band III, all other glycoproteins contain high levels of sialic acid. In addition, human red cells contain glycolipids which have been estimated to be less than 5% of the total lipids. Lanthanum has been used as tracer of extracellular space and as a probe for studies of Ca++metabolism across various types of cellular membrane. Biochemical studies led to the conclusion that lanthanum inhibition of Ca++metabolism was related to the sialic acid content of the cell membrane. The purpose of this communication is to describe the ultrastructural localization of lanthanum in human red cells under various experimental conditions.
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Schedule a callMore From: Proceedings, annual meeting, Electron Microscopy Society of America
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