Lanthanide MOFs based portable fluorescence sensing platform: Quantitative and visual detection of ciprofloxacin and Al3+

Abstract

In the current context of water environmental monitoring and pollution control, there's a crucial need for rapid and simple methods to detect multi-pollutant. We herein report an easy one-step hydrothermal synthesis method to produce Eu-based metal-organic frameworks (Eu MOFs), which was used as a fluorescent probe to detect the aquatic environmental pollutants of ciprofloxacin (CIP) and aluminum ions (Al3+). This fluorescent sensor enabled the cascade detection of CIP and Al3+ through fluorescence enhancement and ratio fluorescence response, respectively. The introduction of CIP significantly turned on the characteristic fluorescence of Eu MOFs at 595 nm and 616 nm through the “antenna effect”. Based on this, the sensor enables quantitative detection of CIP within a linear range of 0–120 μM with a LOD as low as 50.421 nM. In the presence of Al3+, the fluorescence emission of Eu MOFs-CIP was sharply turned off due to strong Al3+ coordination with CIP, while the blue fluorescence emission of CIP was remarkably enhanced. And thus allowing ratio fluorescence quantitative detection of Al3+ (LOD = 2.681 μM). The introduction of CIP and Al3+ in cascade resulted in distinct fluorescence color changes from colorless to red and eventually to blue, exhibiting pronounced fluorescence characteristics. This observable phenomenon enables the visual detection of CIP and Al3+ in both aqueous phase and paper test strips. By combining the analysis of fluorescence chromaticity with the use of a smartphone, the fluorescence color of test papers allows for simple quantitative determination, which provides a convenient and accessible approach for quantifying CIP and Al3+ in water environments.