Abstract
Linguistic and pragmatic skills (comprehension that is context dependent) were examined in 10 right-handed children and adolescents with the continuous spike-waves during slow sleep syndrome (CSWSS) and compared to that of a control population of 36 children, in a study at CHRU de Tours and Universite Francois Rabelais, Tours, France.
Highlights
Evaluation of language skills and longterm outcome are important in the management of epileptic syndromes
Continuous spike-waves during slow sleep syndrome (CSWSS) is a childhood epilepsy characterized by EEG spike waves during at least 85% of slow sleep, and clinically, by neuropsychological and behavioral disorders
continuous spike-waves during slow sleep syndrome (CSWSS) and Landau-Kleffner syndrome are similar in age of onset, mild epilepsy, and severe neuropsychological disorders
Summary
These authors recommend a carefully monitored trial of immediaterelease methylphenidate (MPH) in the treatment of ADHD with comorbid chronic tic disorder (CTD). Larger doses of MPH resulted in minimal increased effectiveness, but with a greater likelihood of tic exacerbation and adverse effects on heart rate, blood pressure and weight. The improved tic control reported by teachers in the classroom, in contrast to the physicians' report of an increase in simple tics with larger doses, may be explained by a student's ability to suppress tics in the stigmatizing school environment.
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