Abstract
Brugada syndrome is a rare inherited channelopathy predisposing to ventricular arrhythmias and leading to an increased risk of sudden cardiac death, despite a structurally normal heart. The most common mutation is a loss-of-function mutation in SCN5A gene, rsesponsible for encoding the α-subunit of the sodium channel. Diagnosis is based on a specific electrocardiogram (ECG) pattern, observed either spontaneously or during a sodium channel blocker test. Considering the two different Brugada pattern types, type 1 is the most frequently associated with the SCN5A gene mutation [1].
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
