Abstract
We are presenting a case of a middle aged male who was a known case of retroviral disease presented with pure red cell aplasia due to lamivudine treatment. The patient was admitted in view of breathlessness on exertion and generalised weakness and fatiguability. On admission, routine blood tests revealed a hemoglobin of 2.3 g/dL with normal leukocyte and platelet counts, indicating single lineage involvement . His blood tests were negative for any autoimmune causes, infective causes like parvo virus and his anaemia persisted even after stopping zidovudine. After stopping lamivudine treatment, the patient’s hemoglobin concentration and hematocrit level returned to normal. In above mentioned case Lamivudine was found to be a cause of pure red cell aplasia.
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