Lamina propria of intestinal mucosa as a typical reticular tissue

Abstract

The three-dimensional architecture of the lamina propria in the jejunal mucosa of the rat was studied by scanning electron microscopy. The lamina propria is a typical reticular tissue with fine nets of reticular fibers and free and fixed cells lying among them. However, the lamina propria in the core of villi displayed structural features closer to other reticular or lymphoid tissues than that among the crypts. In the villi, the tissue was supported by a spongy framework of interconnecting fibroblasts, and densely infiltrated by free cells. Among the crypts, cellular elements were rather sparsely dispersed in a complex network of reticular fibers. A thin layer of reticular fibers lined the basal lamina of the epithelium. This layer contained a network of flattened cells which anastomosed with each other via slender processes. The basal lamina and the fibrous layer were perforated with round pores, through which free cells or basal processes of the epithelial cells passed. Many macrophages were found resting on the reticular framework of the lamina propria, frequently in close association with immunoblast-like cells. This paper further includes scanning electron-microscopic observations on the central lacteal with special reference to its luminal projections and trabeculae.