Lamin-dependent nuclear envelope reassembly following mitosis: an argument

Abstract

During the division of most eukaryotic cells, the nuclear envelope disassembles and subsequently reassembles around the segregated chromosomes to form two new nuclei. With the use of cell-free systems, the molecular mechanisms that underlie this complicated process are beginning to be studied. The importance of nuclear lamins in nuclear envelope reassembly has been controversial for the past five years, but recent findings may help to clarify their role. In this article, we propose a working model for nuclear envelope reassembly.