Lamellar macular holes: the evolution of ideas about pathogenesis and the clinical picture. The development of diagnostic approaches. Modern classification

Abstract

This review presents the development of modern ideas about the pathogenesis of lamellar macular holes, anatomical changes, as well as the formation of a modern classification based on the expansion of diagnostic capabilities, and differences from other similar conditions of the vitreomacular interface. An evolutionary breakthrough in the investigation of this disease was associated with the widespread introduction of optical coherence tomography, while the development of its resolution allowed us to detect some features of epiretinal proliferation that occurs in lamellar macular holes, which are also addressed in the review.