Abstract
High-alcohol drinking (HAD1) and low-alcohol drinking (LAD1) rats were trained to discriminate among 0.75 g/kg ethanol, 1.5 g/kg ethanol and saline under a fixed-ratio 10 schedule. LAD rats learned the discrimination more rapidly than HAD rats, and asymptotic performance by LAD rats was better than that of HAD rats. The 0.75 g/kg dose of ethanol failed to control the responding of HAD rats, both when baseline responding stabilized and during the determination of an ethanol dose-response curve. These differences between LAD and HAD rats in ethanol discrimination were not observed in previous experiments using a two-choice procedure. The three-choice procedure may be useful for establishing strain differences in ethanol discrimination. These and previous experiments with alcohol-preferring rats suggest that the learning of an ethanol discrimination may be dissociable from voluntary ethanol consumption in rat strains bred selectively to consume ethanol.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
