Abstract
To the Editor.— Intestinal lactase activity in childhood can be reduced transiently by several diseases. In developing countries, the most common of these diseases are protein-energy malnutrition and persistent diarrhea. Under these conditions, the use of microbial β-galactosidase for predigestion of dietary lactose is being used as a means of reducing lactose intake while maintaining the quality of the therapeutic diets. In a report by Penny et al,1 the effects of intact and lactose-hydrolyzed formulas on stool output and nutrient absorption in 63 Peruvian children with >4 days of postenteritis diarrhea were compared.
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