Abstract
Letters15 August 1993Lactic Acidosis and AIDSDaniel Baram and Joseph CookeDaniel BaramSearch for more papers by this author and Joseph CookeSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-4-199308150-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In 1991, we had a patient with a clinical course similar to that in the patients described in the recent report by Chattha and coworkers [1], in which a cause of lactic acidosis was found at autopsy. Our patient was a 45-year-old, HIV-positive woman given zidovudine and trimethoprim-sulfamethoxazole. After oral fluconazole therapy for severe oral thrush failed, she was admitted to the hospital for fluids, intravenous fluconazole, and esophageal biopsy after a bout of progressive odynophagia and dehydration. The admission examination was remarkable only for oral thrush and evidence of dehydration. Laboratory values showed a HCO3 level ...
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