Abstract
The lactate acid content of venous blood draining via Labbé's vein from the lateral aspect of the two hemispheres of baboons has been compared. One hemisphere was rendered partially ischaemic by temporary occlusion of the middle cerebral artery and a significant increase in lactic acid content in the draining venous blood was found within 1 min of the occlusion. There was an accompanying significant fall in venous pH. The systemic arterial pH, pO 2 and lactate showed no significant change. It appears that the known prompt increase in cerebral lactic acid content following the establishment of ischaemia is reflected promptly in the lactate content in the draining veins of the infarct.
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