Abstract
Recurrent aphthous ulcers of the mouth are difficult to treat because of no known definite aetiology. This paper presents the use of lactic acid bacteria thought to modulate the host immune response to affect improvements in the disease. Twenty-five patients with the disease were treated with 6 lactic bacteria capsules (in the form of OMX capsules) daily for a period of six months, and their responses were evaluated. Seventeen patients (73.9%) became free of the disease six months later, while 6 (26.1 %) experienced very dramatic improvements. Two patients were lost to follow-up. It is concluded that lactic acid bacteria is beneficial in the treatment of recurrent aphthous ulcers of the mouth.
Highlights
Recurrent aphthous ulcerations of the oral cavity (RAS) is a common disease affecting up to about 25 percent of any population. It is usually classified into 3 types, namely the minor, major and herpetiform aphthous ulcerations
Seventeen patients (73.9%) become totally free of RAS by the end of six months after taking 6 tablets of lactiC ~cld bacteI:Ia (LAB) (OMX) capsules daily, while six patients (26.1 %) did not become totally free of RAS. In these 6 patients there was reduction in the number of ulcers present between 66% to 93% of the original number; reduction in the size of the ulcers between 50% to 83% of the original size; and there was much less pain felt from the ulcers compared to the time before the patient consumed the LAB capsules
Lactic acid bacteria in the form of OMX capsules are beneficial in the treatment of recurrent aphthous ulcers
Summary
Recurrent aphthous ulcerations of the oral cavity (RAS) is a common disease affecting up to about 25 percent of any population. It is usually classified into 3 types, namely the minor, major and herpetiform aphthous ulcerations. The aetiology of RAS is not certain, there are various factors that are thought to play important roles These include allergy to various chemicals and foods, gluten enteropathy, deficiency of blood iron, Vitamin B and folic acid, sensitivity to. Adenoviruses, herp.e~ sim~l~x/ and Stre~tococcus San~llls Type 2A, ~amIlIal tI~~S, psychologIcal and emo~IOnal stress, and 1111lnunologIcal disturbances. It has been sugges~ed that RAS or BD may be caused by human cyt?megalovIrus(l)
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