Abstract
1. 1. Like other lamprey species, Lampetra planeri displays LDH chains of a single type. Since lampreys are more related to vertebrates than myxines, which do have usual A and B monomers, we suspect that either a gene inactivation or a gene loss occurred in the former group. 2. 2. The characterization of the enzyme gave interesting results. From the standpoint of its affinity for ion exchangers, it behaves as if it is composed of A-type chains. 3. 3. From the standpoint of substrate and product inhibition, it resembles much more closely the B containing isozyme. 4. 4. Since literature reports that the other known single-chained LDH's from lampreys are definitely of the A type, we suggest the possibility that L. planeri enzyme underwent some orthologous evolution which brought it to resemble the heart isozyme.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Comparative Biochemistry and Physiology -- Part B: Biochemistry and Molecular Biology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.