Abstract

In this study, the human lacrimal canaliculus (LC), an important segment of the lacrimal drainage system, was imaged using dynamic optical coherence tomography (D-OCT) and the 3D structure of the LC was rendered. In D-OCT system, a turbid commercial ophthalmic solution was used as an extrinsic contrast agent. The lumen boundary of the LC appeared clearer in D-OCT images compared with simple static OCT images, making segmentation easier. D-OCT was performed by calculating the sum of the squared differences of intensities with two different normalization parameters. By color-combining these two D-OCT images and static OCT image, using image calculation software, the contrast agent and the lumen boundary can be clearly separated. 3D volumetric images of the LCs are demonstrated.

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