Abstract
Lack of Systemic Absorption of Topical Mechlorethamine Gel in Patients with Mycosis Fungoides Cutaneous T-Cell Lymphoma
Highlights
Baird DM, Rowson J, Wynford-Thomas D, Kipling D
9 (60) 2 (13.3)1 mechlorethamine gel in patients who did not have a complete response during study 201
During study 201, plasma samples were collected from 23 patients, 16 from the gel arm and 7 from the ointment arm
Summary
Baird DM, Rowson J, Wynford-Thomas D, Kipling D. Olsen E, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, Knobler R, et al Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). 260 patients were enrolled and randomized 1:1 to receive 0.02% mechlorethamine gel or ointment.
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