Abstract
THE messenger hypothesis of genetic control of protein biosynthesis1 suggests that free messenger RNA molecules are present in cells, probably in the cell-sap. Use has been made of cell-free systems to see whether the capability of ordering the sequence of amino-acids in peptides resides in the cell-sap as well as in the ribosomes. Experiments of this type2–5 have been conducted in the same general way. Ribosomes from reticulocytes of one species of animal have been incubated with cell-sap from reticulocytes from a different species and amino-acid incorporation into haemoglobin typical of the species of animal providing the cell-sap has been considered to afford proof that the sap contains messenger RNA. The results have been conflicting; two groups of workers2,5 present evidence which supports this idea while two other groups3,4, using a similar system, find no evidence for such a claim.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
