Abstract
The activities of several of the hepatic mixed function monooxygenase enzymes have been studied in vasectomized and sham-operated rats. The in vitro metabolism of aniline and aminopyrine was slightly but insignificantly depressed in the vasectomized group. Likewise, no significant differences in the hepatic microsomal metabolism of androst-4-en-3,17-dione, or the microsomal content of cytochrome P-450, cytochrome b5, or microsomal protein, were detected between the two groups. In addition, vasectomy appeared to have no effect on the weights of the liver, heart, adrenals, kidneys, or testes.
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