Lack of effect of phenytoin on functions related to Na+,K+-ATPase activity of the intact erythrocytes of epileptic patients.

Abstract

British Journal of Clinical PharmacologyVolume 12, Issue 1 p. 79-81 Free Access Lack of effect of phenytoin on functions related to Na+,K+-ATPase activity of the intact erythrocytes of epileptic patients. JK Aronson, JK AronsonSearch for more papers by this authorDP Geaney, DP GeaneySearch for more papers by this authorDG Grahame-Smith, DG Grahame-SmithSearch for more papers by this authorJC Carver, JC CarverSearch for more papers by this authorKF Hallis, KF HallisSearch for more papers by this author JK Aronson, JK AronsonSearch for more papers by this authorDP Geaney, DP GeaneySearch for more papers by this authorDG Grahame-Smith, DG Grahame-SmithSearch for more papers by this authorJC Carver, JC CarverSearch for more papers by this authorKF Hallis, KF HallisSearch for more papers by this author First published: July 1981 https://doi.org/10.1111/j.1365-2125.1981.tb01858.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References ARONSON, J.K., GRAHAMESMITH, D.G., HALLIS, K.F., HIBBLE, A. & WIGLEY, F. (1977). Monitoring digoxin therapy: I. Plasma concentrations and an in vitro assay of tissue response. Br. J. clin. Pharmac., 4, 213– 221. CUMBERBATCH, M., ZAREIAN, K., DAVIDSON, C., MORGAN, D.B. & SWAMINATHAN, R. (1981). The early and late effects of digoxin treatment on the sodium transport, sodium content and Na+, K+-ATPase of erythrocytes. Br. J. clin. Pharmac. (In press). DEUPREE, J.D. (1977). The role or non-role of ATPase activation by phenytoin in the stabilization of excitable membranes. Epilepsia, 18, 309– 315. FORD, A.R., ARONSON, J.K., GRAHAMESMITH, D.G., ROSE, J.A. (1979a). The characteristics of the binding of 12-α-[3H]-digoxin to the membranes of intact human erythrocytes: relevance to digoxin therapy. Br. J. clin. Pharmac., 8, 115– 124. FORD, A.R., ARONSON, J.K., GRAHAMESMITH, D.G. & CARVER, J.G. (1979b). Changes in cardiac glycoside receptor sites 86rubidium uptake and intracellular sodium concentrations in the erythrocytes of patients receiving digoxin during the early phases of treatment of cardiac failure in regular rhythm and of atrial fibrillation. Br. J. clin. Pharmac., 8, 125– 134. KURATA, D. & WILKINSON, G.R. (1974). Erythrocyte uptake and plasma binding of diphenylhydantoin. Clin. Pharmac. Ther., 16, 355– 362. SCHWOCH, G. & PASSOW, H. (1973). Preparation and properties of human erythrocyte ghosts. Mol. Cell. Biochem., 2, 197– 218. SCOTT, A.K., GILBERT, J.C. & WEBSTER, J. (1980). Anticonvulsants and human erythrocyte ATPase activities. Br. J. clin. Pharmac., 10, 175– 177. Citing Literature Volume12, Issue1July 1981Pages 79-81 ReferencesRelatedInformation