Lack of association of serum resistin levels with metabolic syndrome criteria in obese female patients

Abstract

Background As unclear data of resistin relation with metabolic syndrome has been published, we decide to investigate the association between metabolic syndrome and resistin levels in female obese subjects. Subjects A sample of 551 female obese subjects was analyzed. A complete nutritional and biochemical evaluation was performed. Results Levels of C reactive protein, weight, fat mass and waist circumference were higher in patients in the highest tertile group of resistin than the lowest and middle tertiles of resistin. In the multivariate analysis with metabolic syndrome presence/absence-, only fat mass remained as an independent predictor in the model. Resistin concentration increases 0.020 ng/ml (CI95%:0.006–0.038) for each kg of fat mass in female obese subjects. Conclusion Only fat mass was associated in an independent way. Serum resistin was not associated with the accumulation of MetS factors or the diagnosis of MetS in obese female subjects.