Abstract
Laboratory experiments were undertaken to determine if resistance could be developed in the boll weevil, Anthonomus grandis Boheman, to a representative chemical in each of 3 classes of insecticides now being used for its control. The topical-application technique and insecticide-contaminated larval media were the 2 methods of selection utilized. Selections for resistance to azinphosmethyl and carbaryl, using the contaminated larval media, were unsuccessful. However, selections for resistance utilizing the topical application of the selective insecticides were successful in the cases of endrin and a 2:1 mixture of toxaphene-DDT. Where endrin was used as the selective agent in 1 generation and azinphosmethyl in the next generation for 27 generations, resistance was developed to endrin but not to azinphosmethyl. The most important finding was that the laboratory-developed toxaphene-DDT-resistant culture exhibited cross-resistance to 3 organophosphates (5- to 12-fold) and 2 carbamates (40-fold or greater). Two endrin-resistant cultures exhibited lower levels of cross-resistance to these same materials.
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