Abstract
The search for laboratory markers of depression is currently a potential key to understanding the mechanisms of disease development, selecting personalized antidepressant therapy, and defining clear, specific, and objective diagnostic criteria. Identifying biomarkers of depressive disorder offers a broad field for researching many regulatory systems of the body. The laboratory markers identified so far are involved in neurotrophic, neuroendocrine, neurotransmitter, metabolic, and inflammatory processes. This review discusses the use of various biomarkers for studying depression, focusing on the most promising ones.
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