Abstract
Objective. To determine the role of placental growth factor, fibronectin, certain hemostatic parameters and glycodelin in the genesis of early miscarriage.Materials and methods. Venous blood, inpatient medical records (form No.003/u-07), prenatal records (form No.113/u-07) of 94 pregnant women. The software package "Statistica" 10.0 and the programming language "R" version 4.1 were used for statistical analysis.Results. Placental growth factor, fibronectin and glycodelin can be considered as laboratory markers of miscarriage during the first trimester of gestation.Conclusion. The markers of early reproductive losses we have identified underlie the development of endothelial and hemostasiological disorders and morphofunctional inferiority of the endometrium.
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