Abstract
Label-free optical biosensors have shown promise in rapid and sensitive detection of viruses. Recently, we have demonstrated a technique termed interferometric reflectance imaging sensor (IRIS) capable of detecting viral antigens and single viruses in a high-throughput, quantitative, and label-free fashion. In this paper, we briefly review the current label-free optical methods that have demonstrated virus detection through ensemble measurements of viral antigen and emerging techniques that are capable of detecting individual viruses captured by the sensor. We then present the principle of single nanoparticle detection using IRIS and show proof-of-principle results on specific detection and shape analysis of individual viruses captured on the IRIS platform.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IEEE Journal of Selected Topics in Quantum Electronics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
