Abstract
A sensitive; simple and label-free method for DNA detection is presented. Irradiated polyethylene terephthalate foils were etched to present conical tracks at a density of approximately 5×107 tracks per cm2. Probe DNA was immobilized at the narrow opening of the tracks (2–4nm diameter). The presence of target DNA resulted in changes in both conductance and rectification ratios in a concentration-dependent manner. DNA concentrations as low as 2nM could be detected using this simple two-step detection scheme.
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