Abstract
1. 1. The Cl −/Ca 2+ independent l-[ 3H]glutamate binding sites have been studied in frozen sections of cerebellum and electric lobes of the fish Torpedo marmorata. 2. 2. In vitro autoradiography showed that labelling was concentrated in the molecular layer of cerebellum and homogeneously distributed in the electric lobes. 3. 3. Kinetics of l-[ 3H]glutamate binding revealed a specific and saturable binding in both regions. 4. 4. The pharmacological characterization showed that quisqualate was the most potent displacer of the l-[ 3H]glutamate binding in both regions of Torpedo marmorata brain.
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More From: Comparative Biochemistry and Physiology. Part C, Comparative Pharmacology
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