Abstract

Studies relating to autism spectrum disorders have mainly been carried out in children. However, when children with autism become adult, their handicap continues to put a strain on their everyday life. It is important that health professionals in charge of adult patients consider the possibility of autistic syndrome in patients whose behavior is atypical. Mental disorders may present in a special way in patients with autism spectrum disorders. For instance, depression may produce irritability, aggressive behavior, and change of rituals. Autism spectrum disorders have common features with many other mental disorders, such as schizophrenia and obsessive-compulsive disorders. Our article offers a review of clinical and historical particularities that may help clinicians establish appropriate diagnosis. In this article we focus on clinical features, differential diagnosis, and comorbidity in adult people with autism spectrum disorders. A subsequent article will deal with diagnostic work-up and therapeutic aspects of autism in adult patients.

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