Abstract
Early termination of clinical trials is advisable if initial evidence indicates the treatment under study is ineffective. Predictive probability methods permit the construction of multistage studies that allow for early termination while still controlling overall false-positive (declare an ineffective treatment effective) and false-negative (declare an effective treatment ineffective) error rates. An interactive computer program known as KSTAGE has been developed that aids the researcher in designing such studies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.