Abstract
Background: In 1896 Friedrik Krukenberg described a bilateral ovarian tumor, which he called "mucocellular ovarii fibrosarcoma" (carcinomatodes), considering it to be fibrosarcomatous in nature. Clinical Case: A 22-year-old female patient admitted to the emergency department of our hospital with grade IV anemic syndrome. Two weeks after his admission to the emergency room, he presented melenic evacuations accompanied by asthenia, adynamia, hyporexia and dyspnea. His vital signs were normal except for TA 100/60 mmHg. Their laboratories of admission showed a hemoglobin of 6.3 g rest within normal parameters; Guayaco (++). First Ultrasound reported thickening of the colon walls. His control blood biometry reported hemoglobin of 3.4 g being transfused with globular packages increasing to 12.8 g. Carcinoembryonic antigens reported CA 19.9, 315.27, 15.3 = 7.29. A panendoscopy and colonoscopy was performed, reporting ulcerated lesions in the transverse stenotic colon. It refers to a Regional Hospital of High Specialty to the service of oncology for its integral management. Discussion: Previously, any metastatic ovarian cancer was categorized as Krukenberg's tumor; however, Novak and Gray established new diagnostic criteria to eliminate this confusion. Therefore, a mucin-secreting carcinoma with ring-seal cells in an ovarian fibroblast stroma is a Krukenberg tumor. Most of these tumors are of gastric origin (76%). Colorectal cancers carry a poor 5-year survival prognosis of only 13.1%.
Highlights
In 1896 Friedrik Krukenberg described a bilateral ovarian tumor, which he called "mucocellular ovarii fibrosarcoma", considering it to be fibrosarcomatous in nature
In 1917, special attention was paid to Krukenberg's tumors by finding another bilateral ovarian tumor in a 33-year-old patient with lymphatic involvement but without finding the primary tumor in the digestive tract
The term Krukenberg tumor (TK) indicates only metastatic ovarian cancer originating from another primary tumor, but the WHO has established criteria to establish this diagnosis based on the involvement of stromal tissue with proliferating mucin-producing neoplastic seal ring cells Ovarian stromal sarcomatoid
Summary
In 1896 Friedrik Krukenberg described a bilateral ovarian tumor, which he called "mucocellular ovarii fibrosarcoma" (carcinomatodes), considering it to be fibrosarcomatous in nature. In 1916 Stone drew attention to metastatic cancer emphasizing the possible routes of dissemination to the ovary. In 1917, special attention was paid to Krukenberg's tumors by finding another bilateral ovarian tumor in a 33-year-old patient with lymphatic involvement but without finding the primary tumor in the digestive tract. In 1918 Mayor described blood dissemination by finding tumor cells in the pulmonary circulation during autopsy. Krukenberg in his original report considered the ovarian tumor as primary. In 18 cases they found a primary tumor of the digestive system [1]
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