Abstract

Nearly all gene therapy programs are focused on treating rare diseases caused by a single genetic mutation. Now, a new company, Kriya, has raised $80.5 million in series A funding to develop gene therapies for common diseases, including diabetes. The firm’s three lead therapies will encode insulin growth factor 1 for type 1 diabetes; a glucagon-like peptide 1 receptor agonist for type 2 diabetes and obesity; and insulin and glucokinase for both type 1 and type 2 diabetes. Kriya’s roster includes former leaders of the gene therapy firms AveXis, Roivant Sciences, Sangamo Therapeutics, and Spark Therapeutics.

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