Abstract

Corneal and conjunctival intraepithelial neoplasia (CCIN) is a premalignant lesion of the corneal epithelium and limbus and the most common tumor of the ocular surface. Management of these lesions includes wide local excision followed by supplemental cryotherapy, and topical chemotherapy with antineoplastic drugs. As shown by past research, CCIN has a high recurrence rate after excision alone. Consequently, new chemotherapeutic agents have begun to be used in recent years to reduce the risk of recurrence in recent years. In this case, after a clinical and histopathological diagnosis of CCIN, an interferon alfa-2b (IFN α 2b) eye drop was prepared and used four times daily and complete tumor resolution was noted at the first year. We aimed to present our successful treatment of a case of CCIN with topical IFN α 2b.

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