Abstract
BackgroundDevelopment of a long-term stroke care plan requires serial assessment of long-term patient function and consideration of caregiver mood. However, to date, few comprehensive cohort studies have included both stroke patients and caregivers.Methods/DesignKOSCO is a large, multi-centre prospective cohort study for all acute first-ever stroke patients admitted to participating hospitals in nine distinct areas of Korea. This study is designed as a 10-year, longitudinal follow-up investigating the residual disabilities, activity limitations, and quality of life issues arising in patients suffering from first-ever stroke. The main objectives of this study are to identify the factors that influence residual disability and long-term quality of life. The secondary objectives of this study are to determine the risk of mortality and recurrent vascular events in patients with acute first-ever stroke. We will investigate longitudinal health behaviors and patterns of healthcare utilization, including stroke rehabilitation care. We will also investigate the long-term health status, mood, and quality of life in stroke patient caregivers. In addition, we will identify baseline and ongoing characteristics that are associated with our secondary outcomes.DiscussionKOSCO is a prospective, multi-centre, 10-year longitudinal follow-up study investigating the residual disabilities, activity limitations, and quality of life issues arising in patients suffering from first-ever stroke.
Highlights
Development of a long-term stroke care plan requires serial assessment of long-term patient function and consideration of caregiver mood
Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) is a prospective, multi-centre, 10-year longitudinal follow-up study investigating the residual disabilities, activity limitations, and quality of life issues arising in patients suffering from first-ever stroke
The main objective of this study is to identify the factors that influence long-term residual disabilities, activity limitations, and quality of life in acute first-ever stroke patients
Summary
Development of a long-term stroke care plan requires serial assessment of long-term patient function and consideration of caregiver mood. Many cohort studies of stroke patients have demonstrated the long-term neuropsychological deficits and functional outcomes in United States, Europe, and Asia. Most previous cohort studies have only investigated functional outcomes of stroke during the chronic stage of the disease [10,13]. Stroke recovery is a complex process that probably occurs through a combination of spontaneous and learning-dependent processes, including restitution, substitution, and compensation [14]. This recovery is a dynamic process that cannot be encapsulated at any single timepoint. Long-term prospective studies with long-term assessments in large stroke patient populations are needed in order to rigorously investigate the functional outcomes of this disease
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