Kolesistektomi sonrası kolestaz nedeni olarak Dubin-Johnson sendromu; Olgu sunumu ve literatür incelemesi

Abstract

Dubin Johnson syndrome (DJS), also known as Sprinz-Nelson syndrome is a hereditary disease characterized by conjugated hiperbillirubinemi induced by chronic mild stress. DJS are frequently diagnosed during late adolescence and early adulthood. The patients apply with an itching jaundice, vague abdominal pain, nausea and vomiting. Physical examination is usually accompanied by jaundice, but sometimes hepatomegaly can find out. The disease is usually indolent and does not cause chronic liver failure. Although rifampicin and usodeoksikolik acid may be used in a therapy, the optimal treatment is not still found out. In this article we presented DJS to cause of persistent conjugated hiperbillirubinemi in patient undergoing laparoscopic cholecystectomy because of symptomatic cholelithiasis with literature data