Abstract
Galactofuranosylation has been accomplished with 1-bromo-1-deoxy-2,3,5,6-tetra-O-benzoyl-a-D-galactofuranoside in the presence of cadmium carbonate as promotor. Glycosylation agent has been prepared by bromination of penta-O-benzoyl-ab-D-galactofuranoside with a solution of hydrogen bromide in glacial acetic acid. The precursor of the latter reaction has been produced by benzoylation of D-galactose that had been heated in pyridine while still warm. The following hydroxysteroids have been selected as being representative in terms of configuration, type of hybridization of carbon bearing hydroxyl, position on cyclopentenoperhydrophenantrene nucleus and, implicitly, the degree of shielding: estrone, androstanolone, 11-a-hydroxyprogesterone, prednisolone. The synthesized galactofuranosides have been characterized by 1H and 13C NMR as well as by chromatographic and chemical means.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
