Abstract

Health benefits of Kochujang (KCJ) and its bioactive compounds have been reported in several in vitro and animal studies.ObjectiveThe aim of this study was to investigate the efficacy of KCJ supplementation on body composition and blood lipid profiles in overweight adults.MethodsSixty overweight men and women with BMI ≥23 kg/m2 and waist-hip-ratio (WHR) ≥0.90 for men and ≥0.85 for women were randomly assigned to a KCJ supplement (n=30, 32 g/day) or placebo (n=30, 32 g/day) group for a 12-week, double-blind, placebo controlled study. We measured anthropometric parameters, serum lipid profiles, abdominal fat distribution by computerized tomography and calculated the atherosclerosis indices in 53 subjects (n=26 in KCJ group, n=27 in placebo group) who completed the study.ResultsAfter 12 weeks, the KCJ group showed a significant reduction in visceral fat (cm2) (p<0.05), although body weight (kg) and WHR did not change. Serum concentration of triglycerides and ApoB were decreased when compared to those of the placebo group.ConclusionKCJ supplementation (32 g/day) for 12 weeks in overweight adults showed anti-atherosclerotic and anti-obesogenic effects.Trial registrationClinical trials.gov Identifier: NCT01532375

Highlights

  • The increasing westernized Korean dietary lifestyle, including frequently eating away from home, has favored foods that have not been a part of the traditional Korean diet [1]

  • The remaining 60 subjects were randomly assigned to the KCJ (n=30) and placebo (n=30) groups

  • We found no significant effects on body weight, body fat (%) or WHR after 12 weeks of KCJ supplementation

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Summary

Introduction

The increasing westernized Korean dietary lifestyle, including frequently eating away from home, has favored foods that have not been a part of the traditional Korean diet [1]. The changing consumers’ demand for western food products and diminished traditional dietary lifestyle have overlapped with the prevalence of obesity and obesity-related chronic diseases in Korea [2,3]. Ludy and Mattes [25] reported that hedonically acceptable doses of red pepper altered thermogenesis and appetite. Their findings are consistent with previous reports of Reinbach et al [26] and others [27] who reported the alteration of appetite and energy balance as a result of red pepper or capsaicin intake. Lee et al [28] suggested that the alterations could be through changes in orexigenic and anorexigenic neuropeptides in hypothalamus

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