Abstract

IntroductionComputerized decision support decreases the number of computed tomography pulmonary angiograms (CTPA) for pulmonary embolism (PE) ordered in emergency departments, but it is not always well accepted by emergency physicians. We studied a department-endorsed, evidence-based clinical protocol that included the PE rule-out criteria (PERC) rule, multi-modal education using principles of knowledge translation (KT), and clinical decision support embedded in our order entry system, to decrease the number of unnecessary CTPA ordered.MethodsWe performed a historically controlled observational before-after study for one year pre- and post-implementation of a departmentally-endorsed protocol. We included patients > 18 in whom providers suspected PE and who did not have a contraindication to CTPA. Providers entered clinical information into a diagnostic pathway via computerized order entry. Prior to protocol implementation, we provided education to ordering providers. The primary outcome measure was the number of CTPA ordered per 1,000 visits one year before vs. after implementation.ResultsCTPA declined from 1,033 scans for 98,028 annual visits (10.53 per 1,000 patient visits (95% CI [9.9–11.2]) to 892 scans for 101,172 annual visits (8.81 per 1,000 patient visits (95% CI [8.3–9.4]) p<0.001. The absolute reduction in PACT ordered was 1.72 per 1,000 visits (a 16% reduction). Patient characteristics were similar for both periods.ConclusionKnowledge translation clinical decision support using the PERC rule significantly reduced the number of CTPA ordered.

Highlights

  • Computerized decision support decreases the number of computed tomography pulmonary angiograms (CTPA) for pulmonary embolism (PE) ordered in emergency departments, but it is not always well accepted by emergency physicians

  • We studied a department-endorsed, evidence-based clinical protocol that included the PE rule-out criteria (PERC) rule, multi-modal education using principles of knowledge translation (KT), and clinical decision support embedded in our order entry system, to decrease the number of unnecessary CTPA ordered

  • CTPA declined from 1,033 scans for 98,028 annual visits

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Summary

Introduction

Computerized decision support decreases the number of computed tomography pulmonary angiograms (CTPA) for pulmonary embolism (PE) ordered in emergency departments, but it is not always well accepted by emergency physicians. To enable clinicians to confidently rule out PE while reducing the number of unnecessary CTPAs, several clinical rules have been developed and validated These include the Wells criteria and the Pulmonary Embolism Rule-Out Criteria (PERC).[3,4] A low-probability Wells score, along with a negative D-dimer[5] or a negative PERC score, can rule out a PE with a high enough degree of certainty that the number of patients who would benefit from further testing to increase that certainty would be less than the number harmed by the side effects of the testing itself and the harmful consequences of false-positive results, including needless anticoagulation.[6] Despite clear evidence that the use of validated clinical rules can effectively be used to rule out the diagnosis of PE, anecdotally they are not universally or even commonly applied

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