Abstract

BackgroundVaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths. Despite progress in the field of adolescent health, many young people in Africa still get sick and die from vaccine-preventable diseases due to lack of vaccination. Parents, adolescents and teachers are key players with regard to implementation of adolescent vaccination policies. Therefore, understanding their knowledge, attitudes and practices towards adolescent vaccination may provide clues on what can be done to improve vaccine uptake among adolescents. The aim of this study is to conduct a qualitative and quantitative systematic review on knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa.MethodsWe will include both quantitative and qualitative primary studies. Eligible quantitative studies include both intervention and observational studies. Qualitative studies to be included are focus group discussions, direct observations, in-depth interviews and case ethnographic studies. We will search PubMed, Cochrane Central Register of Controlled Trials, Scopus, Web of Science, WHOLIS, Africa Wide and CINAHL for eligible studies with no time and language limits. We will also check reference lists of included studies for other eligible reports. Two authors will independently screen the search output, select studies and extract data, resolving discrepancies by consensus and discussion. We will analyse qualitative data using thematic analysis where applicable, and quantitative studies findings will be presented in a narrative synthesis form based on the outcomes.DiscussionThe findings from this systematic review will guide the identification of gaps on knowledge, attitudes and practices among the key role players on adolescent vaccination. We anticipate that our findings will guide the development of adolescent-focused vaccination policy in Africa, which is virtually non-existent at present.Systematic review registrationThis review is registered with PROSPERO, registration number CRD42014010395.

Highlights

  • Vaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths

  • Systematic review registration: This review is registered with PROSPERO, registration number CRD42014010395

  • Most systematic reviews rely on randomised control trials (RCTs) and other quantitative evidence, qualitative studies are being increasingly incorporated [39]

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Summary

Introduction

Vaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths. Adolescents and teachers are key players with regard to implementation of adolescent vaccination policies. Understanding their knowledge, attitudes and practices towards adolescent vaccination may provide clues on what can be done to improve vaccine uptake among adolescents. Some vaccines induce short-lived immunity that wanes over time leading to a susceptible population later in life [3,4,5] In such cases, it is recommended that booster doses of the vaccines previously administered in infancy or childhood should be provided later in life (for example during adolescence) to maintain vaccine-induced immunity [3,4,5,6]. Adolescents in these settings have suboptimal immunity against some vaccine-preventable diseases [4]

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