Abstract
Background: Depression is an illness that involves the body, mind, and, thoughts that affect the way a person eats, sleep, feels about him/ her and thinks about things.
 Objectives: The study aimed to assess knowledge, attitude and practice among girls in schools toward Depression, King Saudi Arabia, Khamis Maushyt, the Governate of Aseer Region.
 Methods: Community based cross–sectional descriptive study was conducted in Khamis Mushayt School to identify knowledge, attitude and practice among girls towards depression. A total of 207 students (girls) were involved in the study. They were selected by using simple random sampling techniques. Data were collected through a questionnaire and analyzed using SPSS software version 20.
 Result: The study showed that 180 (87%) students knew what depression means, 151(72.9%) of study group did not feel depressed, while 79 (38.2%) of the study group sometimes felt lonely. In the study, 50 (24.2%) of students go to the physician when they feel depressed and 53 (25.6%) students in the study group think that depression has medical treatment while 109 (52.7%) of study group believed that depression might have other treatment such as Holy Qur’an.
 Conclusion: There is a need for a national intervention program to promote of adolescent mental health in schools. The program should include the screening of students using psychometric scales.
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