Abstract
We have previously identified differences between fibroblasts isolated from normal peritoneum and from adhesions, and have identified phenotype differences between these two cell types from the same patients. Specifically, we have shown that adhesion fibroblasts manifest significantly higher levels of type I collagen and TGF-β1, but with lower nitric oxide levels as compared to normal peritoneal fibroblasts. Our objective is to determine the effects of knocking-out the expression of iNOS in human fibroblasts isolated from normal peritoneal and adhesion tissues on the expression levels of type I collagen and TGF-β1.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
