Abstract
ABSTRACT To evaluate knee and ankle disorders during functional gait assessment in individuals with Mucopolysaccharidosis type VI (MPS VI). 19 subjects were included in this cross-sectional study and allocated in three groups according to age: Children Group (n=11); Adolescent Group (n=4); and Adult Group (n=4). Subphases of one gait cycle were analyzed: Initial contact; Medium support, and Pre-Balance. All volunteers with MPS VI presented greater knee and ankle flexion angles, in all gait subphases, when compared to the normal values defined by literature (p<0.05). Initial contact subphase: knee flexion angle ranging from 8.5º to 15º; Ankle = Child Group −23.73º ± 8.53º; Adolescent Group = −25º ± 11.22º; Adult Group = −27.75º ± 3.3º. Medium support subphase: Knee = Child Group 19.64º ± 10.47º; Adolescent Group 16.75º ± 10.34º; Adult Group = 21.25º ± 12.84º. Ankle = Child Group −18.82º ± 8.91º ± 8.53º; Adolescent Group = −16.5º ± 9.33º; Adult Group = −22.25º ± 4.19º. Pre-Balance subphase: Knee = Child Group 22.72º ± 13.49º; Adolescent Group 21.25º ± 7.97º; Adult Group = 27º ± 16.27º. Ankle = Child Group -15º ± 9.76º; Adolescent Group = −15.75º ± 5.31º; Adult Group = −14.75º ± 3.86º. In this study, MPS VI individuals presented hyperflexion of knee and ankle as the main joint disorders during functional gait, regardless of age.
Highlights
METHODOLOGYMucopolysaccharidosis type VI (MPS VI), known as Maroteaux-Lamy syndrome, is characterized by progressive autosomal recessive lysosomal storage deficiency with multisystemic involvement[1]
This study evaluates knee and ankle disorders during functional gait assessment in individuals with Mucopolysaccharidosis type VI (MPS VI)
All evaluations were performed with patients dressed in light clothing, in order to allow the observation of the five markers placed on the anatomical points of the lower limbs
Summary
Mucopolysaccharidosis type VI (MPS VI), known as Maroteaux-Lamy syndrome, is characterized by progressive autosomal recessive lysosomal storage deficiency with multisystemic involvement[1]. This study evaluates knee and ankle disorders during functional gait assessment in individuals with Mucopolysaccharidosis type VI (MPS VI). All evaluations were performed with patients dressed in light clothing, in order to allow the observation of the five markers placed on the anatomical points of the lower limbs (head of the V metatarsus, below the central point of the lateral malleolus, head of the fibula, lateral condyle of the femur, and greater trochanter of the femur) These marks allowed to measure the angles of the movements of the sagittal plane of the knee joint (flexion and extension) and of the ankle (plantar flexion and dorsiflexion). Intra- and inter-examiner tests were not performed, as the evaluators were always the same and did not change their function during collection
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
