Abstract
Symptoms of normal-pressure hydrocephalus (NPH) and the complete Klüver-Bucy syndrome (KBS) developed in a previously healthy woman before the appearance of ventricular dilatation on computerized tomography. Ventricular enlargement typical of NPH occurred several months later. Following ventriculoperitoneal shunting, gait abnormalities and KBS resolved, while incontinence, memory, and intellect improved and have since remained stable. An associated sleep disturbance characterized by early onset of rapid-eye movement (REM) sleep periods and sleep spindles throughout REM sleep was also improved by treatment. NPH may impair periventricular function before ventricular dilatation becomes apparent.
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