Abstract

Researchers at Medical College of Georgia, Augusta, GA, report a 10-year-old girl with a history of Listeria monocytogenes meningoencephalitis, contracted at 2½ years of age, who developed behavioral changes consistent with Kluver-Bucy syndrome at 2 months following discharge.

Highlights

  • Researchers at Medical College of Georgia, Augusta, GA, report a 10-year-old girl with a history of Listeria monocytogenes meningoencephalitis, contracted at 2Vi years of age, who developed behavioral changes consistent with Kluver-Bucy syndrome

  • Compared to plasma exchange (PLEX), patients treated with intravenous immunoglobulin (IVIG) have similar clinical outcome and lower costs of hospitalization

  • A review of the literature from 1960 to 2009 uncovered 18 articles concerning response to thymectomy in children with myasthenia gravis (MG), and a total of 479 patients of whom 68% showed improvement and 39% had discontinued medication

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Summary

Introduction

Researchers at Medical College of Georgia, Augusta, GA, report a 10-year-old girl with a history of Listeria monocytogenes meningoencephalitis, contracted at 2Vi years of age, who developed behavioral changes consistent with Kluver-Bucy syndrome. Clinical and economic outcomes following plasma exchange (PLEX) and intravenous immunoglobulin (IVIG) in 1,606 hospitalized adult patients with myasthenia gravis (MG) were compared in a study at Case Western Reserve University, Cleveland, OH; St Louis University, MO; and University of Alabama, Birmingham, AL. MG crisis patients (n=698) had higher mortality and complication rates, and those receiving PLEX (n=529) had significantly more complications than those receiving IVIG (169).

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