Abstract

The present study aims to retrospectively analyze the frequency, demographic characteristics, affecting risk factors and outcomes of intra-uterine fetal death (IUFD) cases delivered between 2015 and 2022 in our clinic, a tertiary center. Between January 2015 and December 2021, 92 pregnant women between 22-41 weeks of gestational age who gave birth due to IUFD in Muğla University Education and Research Hospital clinic were included in the study. Age at presentation, gravida, parity and body mass index (BMI) data, gestational weeks, and if after birth, birth weight, mode of delivery, infant sex and pathologic examination results were recorded. There were 92 cases of IUFD between the specified dates. The ratio of cases to the number of births was 1.03%. Of the cases, 88 (95.65%) were singleton pregnancies and 4 (4.34%) were multiple pregnancies. The mean age was 29.47±5.71 years. Among the cases, 1 (1.08%) pregnant woman was under 18 years of age and 1 pregnant woman was over 40 years of age. The mean BMI was 25.54±3.90 kg/m2 and 2 (2.16%) pregnant women were morbidly obese (≥40 kg/m2). The mean gestational age was 31.07±4.87 weeks. When the causes of IUFD were evaluated, placental abruptio1n was observed in 12 (13.18%) pregnant women. Hypertensive disorders of pregnancy were present in 6 (50%) of the pregnant women with placental abruption. While 5 (5.49%) pregnant women had diabetes mellitus, 2 (2.19%) had placenta previa. A total of 7 (7.60%) pregnant women had anhydroamniosis, a sign of uteroplacental insufficiency, during hospitalization, while 20 (21.97%) pregnant women had fetal anomaly. One (1.09%) pregnant woman developed disseminated intravascular coagulation. In addition, 3 (3.26%) pregnant women had COVID-19 and were hospitalized. The predictability of IUFD cases is low. But despite this, each center can partially reduce the incidence of IUFD with a pro-active approach by evaluating its own outcomes and identifying risk factors.

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