Abstract

IN 1956 Tjio and Levan1 and Ford and Hamerton2 conclusively established the normal human chromosome number to be 46. This number includes 22 pairs of autosomes and 2 sex chromosomes, paired in the female (XX) and unpaired in the male (XY). In 1959 abnormal numbers of chromosomes were described in several clinical entities. In mongolism 47 chromosomes were found,3 with 3 of 1 of the small autosomes in place of the usual pair. Klinefelter's syndrome (testicular dysgenesis) is also associated with 47 chromosomes,4 owing to the presence of 3 sex chromosomes (XXY). Patients with Turner's syndrome (ovarian agenesis) have only . . .

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.