Abstract
Kleine-Levin syndrome (KLS) is a rare disorder characterised by hypersomnia, hyperphagia and behavioural disturbances. It typically occurs in adolescent men and may mimic a variety of neuropsychiatric conditions. Here we report what appears to be the first published case of KLS in South Africa and trace the clinical course, investigations and diagnostic difficulties encountered in the management of this condition. An overview of the literature guiding the diagnosis, differentials and treatment is discussed.
Highlights
Kleine-Levin syndrome (KLS) is considered an excep tionally rare,[1] recurrent condition characterised by hypersomnia, hyperphagia and behavioural disturbances including hypersexuality, depression, irritability and derealisation.[1,2]
This paper describes a case of typical KLS, the first to be documented in South Africa (SA), and illustrates diagnostic difficulties in its presentation
This report appears to be the first published case in SA of an adolescent with KLS presenting with neuropsychiatric symptoms to an acute psychiatric service
Summary
Kleine-Levin syndrome as a neuropsychiatric presentation: A case report and review. Kleine-Levin syndrome (KLS) is a rare disorder characterised by hypersomnia, hyperphagia and behavioural disturbances. It typically occurs in adolescent men and may mimic a variety of neuropsychiatric conditions. We report what appears to be the first published case of KLS in South Africa and trace the clinical course, investigations and diagnostic difficulties encountered in the management of this condition. Kleine-Levin syndrome (KLS) is considered an excep tionally rare,[1] recurrent condition characterised by hypersomnia, hyperphagia and behavioural disturbances including hypersexuality, depression, irritability and derealisation.[1,2] It occurs typically in adolescent men, who are often misdiagnosed with depression, bipolar disorder, psy chosis or seizure disorders. This paper describes a case of typical KLS, the first to be documented in South Africa (SA), and illustrates diagnostic difficulties in its presentation
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